Michael Cahalan, Ph.D.


T-Cell Activation; Calcium Signaling; Imaging Lymphocyte Dynamics In Vitro and In Vivo

Research Interests

Dr. Cahalan's lab is pursuing a single-cell approach to Immunology, using techniques that provide dynamic monitoring of functions in living T cells. Toward this goal, Dr. Cahalan states that his researchers are using the patch-clamp technique to monitor ion channel activity in single T cells; calcium imaging to determine the pattern of signaling evoked by stimulation of the T cell receptor; gene expression probes to visualize activation in single cells; and two-photon microscopy to see cells in intact lymphoid organs.



285 Irvine Hall
(949) 824-7776


285 Irvine Hall
(949) 824-6754