NIH Training Grant Fellow: Evelyn Hoover

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Evelyn Hoover is an MD/PhD candidate in the Lodoen Lab in the Department of Molecular Biology and Biochemistry at UC Irvine. She received her BS in Microbiology from the Texas A&M University in College Station in 2013. Her long term research interests involve deciphering host-microbial interactions, in order to help develop novel therapeutics. Prior to joining the Lodoen lab Evelyn worked in the Raffatellu lab to elucidate how bacterial zinc acquisition systems in the probiotic bacteria Escherichia coli Nissle 1917 help to ameliorate infections with Salmonella enterica serovar Typhimurium, a leading cause of foodborne illness worldwide. 

Currently, Evelyn is examining how the pathogen Toxoplasma gondii interacts with the host immune system. T. gondii is a widely successful parasite, chronically infecting ~35 percent of the global population. No vaccine or cure exists for the chronic infection. Her project currently has two major fronts: first to examine how the host defends against vascular injury and second to understand how the immune landscape differs between organs during infection with T. gondii

Publications:

Hoose, S. A., Duran, C., Malik, I., Eslamfam, S., Shasserre, S. C., Downing, S. S., Hoover, E. M. et al. Systematic analysis of cell cycle effects of common drugs leads to the discovery of a suppressive interaction between gemfibrozil and fluoxetine. PloS One 7, e36503 (2012).

Hoose, S. A., Rawlings, J. A., Kelly, M. M., Leitch, M. C., Ababneh, Q. O., Robles, J. P., Taylor, D., Hoover, E. M. et al. A systematic analysis of cell cycle regulators in yeast reveals that most factors act independently of cell size to control initiation of division. PLoS Genetics 8, e1002590 (2012).

Honors and Awards:

2016- NIH Immunology Research Training Program Grant T32 AI 60573

2013- Graduated Magna Cum Laude from Texas A&M University

2013- Undergraduate Research Fellow, Texas A&M University

2013- University and Foundation Honors, Texas A&M University

2012- DAAD RISE Scholarship, Germany

2009-2013- National Hispanic Merit Scholarship, Texas A&M University